Targeting CD133 improves chemotherapeutic efficacy of recurrent pediatric pilocytic astrocytoma following prolonged chemotherapy

BACKGROUND: Pilocytic astrocytomas (PAs) are the most common pediatric central nervous system neoplasms. In the majority of cases these tumors are benign and receive favorable prognosis following gross total surgical resection. In patients with progressive or symptomatic tumors, aggressive surgical...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Xi, Guifa, Li, Yuping Derek, Grahovac, Gordan, Rajaram, Veena, Wadhwani, Nitin, Pundy, Tatiana, Mania-Farnell, Barbara, James, Charles David, Tomita, Tadanori
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282778/
https://ncbi.nlm.nih.gov/pubmed/28137267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0593-z
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