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Modeling Herpes Simplex Virus 1 Infections in Human Central Nervous System Neuronal Cells Using Two- and Three-Dimensional Cultures Derived from Induced Pluripotent Stem Cells

Herpes simplex virus 1 (HSV-1) establishes latency in both peripheral nerve ganglia and the central nervous system (CNS). The outcomes of acute and latent infections in these different anatomic sites appear to be distinct. It is becoming clear that many of the existing culture models using animal pr...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: D’Aiuto, Leonardo, Bloom, David C., Naciri, Jennifer N., Smith, Adam, Edwards, Terri G., McClain, Lora, Callio, Jason A., Jessup, Morgan, Wood, Joel, Chowdari, Kodavali, Demers, Matthew, Abrahamson, Eric E., Ikonomovic, Milos D., Viggiano, Luigi, De Zio, Roberta, Watkins, Simon, Kinchington, Paul R., Nimgaonkar, Vishwajit L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475775/
https://ncbi.nlm.nih.gov/pubmed/30787148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00111-19
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