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ATP release into ADPKD cysts via pannexin-1/P2X7 channels decreases ENaC activity

Genetic predisposition is necessary for polycystic kidney disease (PKD) initiation, although there are other, incompletely identified downstream processes that are required for cyst growth. Their characterization may provide a unique opportunity for clinical interventions. One of the poorly studied...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Arkhipov, Sergey N., Pavlov, Tengis S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475605/
https://ncbi.nlm.nih.gov/pubmed/30952430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.03.177
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