A Natural Killer/Dendritic Cell Axis Defines Responsive Tumor Microenvironments in Melanoma

Intratumoral stimulatory dendritic cells (SDCs) play an important role in stimulating cytotoxic T cells and driving immune responses against cancer. Understanding the mechanisms that regulate their abundance in the tumor microenvironment (TME) could unveil new therapeutic opportunities. We find that...

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Publicado no:Nat Med
Main Authors: Barry, Kevin C., Hsu, Joy, Broz, Miranda L., Cueto, Francisco J., Binnewies, Mikhail, Combes, Alexis J., Nelson, Amanda E., Loo, Kimberly, Kumar, Raj, Rosenblum, Michael D., Alvarado, Michael D., Wolf, Denise M., Bogunovic, Dusan, Bhardwaj, Nina, Daud, Adil I., Ha, Patrick K., Ryan, William R., Pollack, Joshua L., Samad, Bushra, Asthana, Saurabh, Chan, Vincent, Krummel, Matthew F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475503/
https://ncbi.nlm.nih.gov/pubmed/29942093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0085-8
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