A Natural Killer/Dendritic Cell Axis Defines Responsive Tumor Microenvironments in Melanoma

Intratumoral stimulatory dendritic cells (SDCs) play an important role in stimulating cytotoxic T cells and driving immune responses against cancer. Understanding the mechanisms that regulate their abundance in the tumor microenvironment (TME) could unveil new therapeutic opportunities. We find that...

Full description

Saved in:
Bibliographic Details
Published in:Nat Med
Main Authors: Barry, Kevin C., Hsu, Joy, Broz, Miranda L., Cueto, Francisco J., Binnewies, Mikhail, Combes, Alexis J., Nelson, Amanda E., Loo, Kimberly, Kumar, Raj, Rosenblum, Michael D., Alvarado, Michael D., Wolf, Denise M., Bogunovic, Dusan, Bhardwaj, Nina, Daud, Adil I., Ha, Patrick K., Ryan, William R., Pollack, Joshua L., Samad, Bushra, Asthana, Saurabh, Chan, Vincent, Krummel, Matthew F.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475503/
https://ncbi.nlm.nih.gov/pubmed/29942093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0085-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items