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Heterologous and in vitro reconstitution of fuscanodin, a lasso peptide from Thermobifida fusca
Lasso peptides are a class of ribosomally-derived natural products typified by their threaded rotaxane structure. The conversion of a linear precursor peptide into a lasso peptide structure requires two enzymatic activities: cleavage of the precursor via a cysteine protease and cyclization via isope...
Gardado en:
| Publicado en: | J Am Chem Soc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6475475/ https://ncbi.nlm.nih.gov/pubmed/30532970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b10724 |
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