Hepatic posttranscriptional network comprised of CCR4–NOT deadenylase and FGF21 maintains systemic metabolic homeostasis

Whole-body metabolic homeostasis is tightly controlled by hormone-like factors with systemic or paracrine effects that are derived from nonendocrine organs, including adipose tissue (adipokines) and liver (hepatokines). Fibroblast growth factor 21 (FGF21) is a hormone-like protein, which is emerging...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Morita, Masahiro, Siddiqui, Nadeem, Katsumura, Sakie, Rouya, Christopher, Larsson, Ola, Nagashima, Takeshi, Hekmatnejad, Bahareh, Takahashi, Akinori, Kiyonari, Hiroshi, Zang, Mengwei, St-Arnaud, René, Oike, Yuichi, Giguère, Vincent, Topisirovic, Ivan, Okada-Hatakeyama, Mariko, Yamamoto, Tadashi, Sonenberg, Nahum
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475422/
https://ncbi.nlm.nih.gov/pubmed/30926667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816023116
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