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Loss of postnatal quiescence of neural stem cells through mTOR activation upon genetic removal of cysteine string protein-α

Neural stem cells continuously generate newborn neurons that integrate into and modify neural circuitry in the adult hippocampus. The molecular mechanisms that regulate or perturb neural stem cell proliferation and differentiation, however, remain poorly understood. Here, we have found that mouse hi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nieto-González, Jose L., Gómez-Sánchez, Leonardo, Mavillard, Fabiola, Linares-Clemente, Pedro, Rivero, María C., Valenzuela-Villatoro, Marina, Muñoz-Bravo, José L., Pardal, Ricardo, Fernández-Chacón, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475374/
https://ncbi.nlm.nih.gov/pubmed/30926666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817183116
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