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mTOR and metabolic pathways in T cell quiescence and functional activation

The mechanistic target of rapamycin (mTOR), an evolutionally conserved serine and threonine kinase, plays a critical role in the promotion of cell growth and proliferation via integration of cellular and environmental cues. In adaptive immunity, the mTOR pathway orchestrates multiple physiological p...

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Detalhes bibliográficos
Main Authors: Yang, Kai, Chi, Hongbo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855395/
https://ncbi.nlm.nih.gov/pubmed/23375549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2012.12.004
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