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mTOR and metabolic pathways in T cell quiescence and functional activation
The mechanistic target of rapamycin (mTOR), an evolutionally conserved serine and threonine kinase, plays a critical role in the promotion of cell growth and proliferation via integration of cellular and environmental cues. In adaptive immunity, the mTOR pathway orchestrates multiple physiological p...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855395/ https://ncbi.nlm.nih.gov/pubmed/23375549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2012.12.004 |
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