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Enantioselective Synthesis of 4-Methyl-3,4-dihydroisocoumarin via Asymmetric Hydroformylation of Styrene Derivatives

[Image: see text] Enantioenriched aldehydes are produced through asymmetric hydroformylation of styrene derivatives using BIBOP type ligands. The featured example is enantioselective synthesis of 4-methyl-3,4-dihydroisocoumarin, which was prepared in a 95.1:4.9 enantiomeric ratio from asymmetric hyd...

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Detalles Bibliográficos
Publicado en:J Org Chem
Autores principales: Qu, Bo, Tan, Renchang, Herling, Madison R., Haddad, Nizar, Grinberg, Nelu, Kozlowski, Marisa C., Zhang, Xumu, Senanayake, Chris H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474792/
https://ncbi.nlm.nih.gov/pubmed/30779574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.8b02813
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