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Detection of Low-Abundance Metabolites in Live Cells Using an RNA Integrator

Genetically encoded biosensors are useful tools for detecting the presence and levels of diverse biomolecules in living cells. However, low-abundance targets are difficult to detect because they are often unable to bind and activate enough biosensors to detect using standard microscopic imaging appr...

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Bibliographic Details
Published in:Cell Chem Biol
Main Authors: You, Mingxu, Litke, Jacob L., Wu, Rigumula, Jaffrey, Samie R.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474789/
https://ncbi.nlm.nih.gov/pubmed/30773480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.01.005
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