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Detection of Low-Abundance Metabolites in Live Cells Using an RNA Integrator

Genetically encoded biosensors are useful tools for detecting the presence and levels of diverse biomolecules in living cells. However, low-abundance targets are difficult to detect because they are often unable to bind and activate enough biosensors to detect using standard microscopic imaging appr...

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Publicat a:Cell Chem Biol
Autors principals: You, Mingxu, Litke, Jacob L., Wu, Rigumula, Jaffrey, Samie R.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474789/
https://ncbi.nlm.nih.gov/pubmed/30773480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.01.005
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