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Fragment-based screening of programmed death ligand 1 (PD-L1)
The PD-1 immune checkpoint pathway is a highly validated target for cancer immunotherapy. Despite the potential ad-vantages of small molecule inhibitors over antibodies, the discovery of small molecule checkpoint inhibitors has lagged behind. To discover small molecule inhibitors of the PD-1 pathway...
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| Publicado no: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6474755/ https://ncbi.nlm.nih.gov/pubmed/30728114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.01.028 |
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