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Bioactive sphingolipid profile in a xenograft mouse model of head and neck squamous cell carcinoma

The purpose of this study was to determine the profile of bioactive sphingolipids in xenograft mouse tissues of head and neck squamous cell carcinoma. We utilized UHPLC-MS/MS to determine the profile of full set of ceramides, sphingosine, and sphingosine 1-phosphate in this xenograft mouse model. Th...

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Veröffentlicht in:PLoS One
Hauptverfasser: Bai, Aiping, Liu, Xiang, Bielawski, Jacek, Hannun, Yusuf A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474618/
https://ncbi.nlm.nih.gov/pubmed/31002723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215770
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