Metabolic modulation of acetaminophen-induced hepatotoxicity by osteopontin

Induction of osteopontin (OPN), a well-known pro-inflammatory molecule, has been observed in acetaminophen (APAP)-induced hepatotoxicity. However, the precise cell source for OPN induction and its role during APAP-induced hepatotoxicity has not been fully explored. By employing a hepatotoxic mouse m...

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Publicat a:Cell Mol Immunol
Autors principals: Wen, Yankai, Wang, Chenchen, Gu, Jinyang, Yu, Chang, Wang, Kaixia, Sun, Xuehua, Sun, Yun, Wu, Hailong, Tong, Ying, Xia, Qiang, Kong, Xiaoni
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474212/
https://ncbi.nlm.nih.gov/pubmed/29735980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-018-0033-z
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