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The dual role of osteopontin in acetaminophen hepatotoxicity
AIM: Osteopontin (OPN), a multifunctional protein, has been reported to be protoxicant in acetaminophen hepatotoxicity. In this study, the mechanisms underlying the detrimental role of OPN in acetaminophen toxicity were explored. METHODS: Male C57BL/6 (wild-type, WT) and OPN(−/−) mice were administe...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4011331/ https://ncbi.nlm.nih.gov/pubmed/22728710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.47 |
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