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Defective Initiation of Liver Regeneration in Osteopontin-Deficient Mice after Partial Hepatectomy due to Insufficient Activation of IL-6/Stat3 Pathway

The initial process in liver regeneration after partial hepatectomy involves the recruitment of immune cells and the release of cytokines. Osteopontin (OPN), a pro-inflammatory protein, plays critical roles in immune cell activation and migration. Although OPN has been implicated in the pathogenesis...

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Detalles Bibliográficos
Publicado en:Int J Biol Sci
Main Authors: Wen, Yankai, Feng, Dechun, Wu, Hailong, Liu, Wenjun, Li, Hongjie, Wang, Fang, Xia, Qiang, Gao, Wei-Qiang, Kong, Xiaoni
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551759/
https://ncbi.nlm.nih.gov/pubmed/26327817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.12118
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