TREM-1 multimerization is essential for its activation on monocytes and neutrophils

The triggering receptor expressed on myeloid cells-1 (TREM-1) is a receptor expressed on innate immune cells. By promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptors (TLRs), TREM-1 has been characterized as a major player in the pathophysiology of a...

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Vydáno v:Cell Mol Immunol
Hlavní autoři: Carrasco, Kevin, Boufenzer, Amir, Jolly, Lucie, Le Cordier, Helene, Wang, Guanbo, Heck, Albert JR, Cerwenka, Adelheid, Vinolo, Emilie, Nazabal, Alexis, Kriznik, Alexandre, Launay, Pierre, Gibot, Sebastien, Derive, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474208/
https://ncbi.nlm.nih.gov/pubmed/29568119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-018-0003-5
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