Triggering Receptor Expressed on Myeloid Cells-1 Inhibitor Targeted to Endothelium Decreases Cell Activation

TREM-1 (Triggering Receptor Expressed on Myeloid cells-1) is an immunoreceptor expressed on neutrophils, monocytes/macrophages, and endothelial cells. It amplifies the inflammatory response driven by Toll-Like Receptors (TLR) engagement. The pharmacological inhibition of TREM-1 confers protection in...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gibot, Sébastien, Jolly, Lucie, Lemarié, Jérémie, Carrasco, Kevin, Derive, Marc, Boufenzer, Amir
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779727/
https://ncbi.nlm.nih.gov/pubmed/31632399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02314
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