MAW point mutation impairs H. Seropedicae RecA ATP hydrolysis and DNA repair without inducing large conformational changes in its structure

RecA is a multifunctional protein that plays a central role in DNA repair in bacteria. The structural Make ATP Work motif (MAW) is proposed to control the ATPase activity of RecA. In the present work, we report the biochemical activity and structural effects of the L53Q mutation at the MAW motif of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Leite, Wellington C., Penteado, Renato F., Gomes, Fernando, Iulek, Jorge, Etto, Rafael M., Saab, Sérgio C., Steffens, Maria B. R., Galvão, Carolina W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472873/
https://ncbi.nlm.nih.gov/pubmed/30998678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214601
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge