MAW point mutation impairs H. Seropedicae RecA ATP hydrolysis and DNA repair without inducing large conformational changes in its structure

RecA is a multifunctional protein that plays a central role in DNA repair in bacteria. The structural Make ATP Work motif (MAW) is proposed to control the ATPase activity of RecA. In the present work, we report the biochemical activity and structural effects of the L53Q mutation at the MAW motif of...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Leite, Wellington C., Penteado, Renato F., Gomes, Fernando, Iulek, Jorge, Etto, Rafael M., Saab, Sérgio C., Steffens, Maria B. R., Galvão, Carolina W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472873/
https://ncbi.nlm.nih.gov/pubmed/30998678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214601
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