Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1

Dishevelled (DVL) is the key component of the Wnt signaling pathway. Currently, DVL conformational dynamics under native conditions is unknown. To overcome this limitation, we develop the Fluorescein Arsenical Hairpin Binder- (FlAsH-) based FRET in vivo approach to study DVL conformation in living c...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Harnoš, Jakub, Cañizal, Maria Consuelo Alonso, Jurásek, Miroslav, Kumar, Jitender, Holler, Cornelia, Schambony, Alexandra, Hanáková, Kateřina, Bernatík, Ondřej, Zdráhal, Zbyněk, Gömöryová, Kristína, Gybeľ, Tomáš, Radaszkiewicz, Tomasz Witold, Kravec, Marek, Trantírek, Lukáš, Ryneš, Jan, Dave, Zankruti, Fernández-Llamazares, Ana Iris, Vácha, Robert, Tripsianes, Konstantinos, Hoffmann, Carsten, Bryja, Vítězslav
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472409/
https://ncbi.nlm.nih.gov/pubmed/31000703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09651-7
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi