Bromocriptine and cabergoline induce cell death in prolactinoma cells via the ERK/EGR1 and AKT/mTOR pathway respectively

The treatment of hyperprolactinemia is based on the use of dopamine agonists, mainly bromocriptine (BRC) and cabergoline (CAB). They reduce tumour size effectively and restore gonadal function. However, there is a difference in drug sensitivity between CAB and BRC in patients with prolactinoma, alth...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Tang, Chao, Sun, Ruixin, Wen, Guodao, Zhong, Chunyu, Yang, Jin, Zhu, Junhao, Cong, Zixiang, Luo, Xiaoying, Ma, Chiyuan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472389/
https://ncbi.nlm.nih.gov/pubmed/31000722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1526-0
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