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Bromocriptine and cabergoline induce cell death in prolactinoma cells via the ERK/EGR1 and AKT/mTOR pathway respectively

The treatment of hyperprolactinemia is based on the use of dopamine agonists, mainly bromocriptine (BRC) and cabergoline (CAB). They reduce tumour size effectively and restore gonadal function. However, there is a difference in drug sensitivity between CAB and BRC in patients with prolactinoma, alth...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Death Dis
मुख्य लेखकों: Tang, Chao, Sun, Ruixin, Wen, Guodao, Zhong, Chunyu, Yang, Jin, Zhu, Junhao, Cong, Zixiang, Luo, Xiaoying, Ma, Chiyuan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472389/
https://ncbi.nlm.nih.gov/pubmed/31000722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1526-0
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