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Bromocriptine and cabergoline induce cell death in prolactinoma cells via the ERK/EGR1 and AKT/mTOR pathway respectively

The treatment of hyperprolactinemia is based on the use of dopamine agonists, mainly bromocriptine (BRC) and cabergoline (CAB). They reduce tumour size effectively and restore gonadal function. However, there is a difference in drug sensitivity between CAB and BRC in patients with prolactinoma, alth...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Tang, Chao, Sun, Ruixin, Wen, Guodao, Zhong, Chunyu, Yang, Jin, Zhu, Junhao, Cong, Zixiang, Luo, Xiaoying, Ma, Chiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472389/
https://ncbi.nlm.nih.gov/pubmed/31000722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1526-0
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