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Overexpression of ribonuclease inhibitor induces autophagy in human colorectal cancer cells via the Akt/mTOR/ULK1 pathway

Ribonuclease inhibitor (RI), also termed angiogenin inhibitor, acts as the inhibitor of ribonucleolytic activity of RNase A and angiogenin. The expression of RI has been investigated in melanoma and bladder cancer cells. However, the precise role of RI in tumorigenesis, in addition to RI-induced aut...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Med Rep
Hauptverfasser: Tang, Ying, Ren, Feng, Cong, Xi, Kong, Ying, Tian, Yuxiang, Xu, Yuefei, Fan, Jianhui
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472130/
https://ncbi.nlm.nih.gov/pubmed/30896869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10030
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