Rapamycin Upregulates Autophagy by Inhibiting the mTOR-ULK1 Pathway, Resulting in Reduced Podocyte Injury

The podocyte functions as a glomerular filtration barrier. Autophagy of postmitotic cells is an important protective mechanism that is essential for maintaining the homeostasis of podocytes. Exploring an in vivo rat model of passive Heymann nephritis and an in vitro model of puromycin amino nucleoti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wu, Lingling, Feng, Zhe, Cui, Shaoyuan, Hou, Kai, Tang, Li, Zhou, Jianhui, Cai, Guangyan, Xie, Yuansheng, Hong, Quan, Fu, Bo, Chen, Xiangmei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648526/
https://ncbi.nlm.nih.gov/pubmed/23667674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063799
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