Rapamycin Upregulates Autophagy by Inhibiting the mTOR-ULK1 Pathway, Resulting in Reduced Podocyte Injury

The podocyte functions as a glomerular filtration barrier. Autophagy of postmitotic cells is an important protective mechanism that is essential for maintaining the homeostasis of podocytes. Exploring an in vivo rat model of passive Heymann nephritis and an in vitro model of puromycin amino nucleoti...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Wu, Lingling, Feng, Zhe, Cui, Shaoyuan, Hou, Kai, Tang, Li, Zhou, Jianhui, Cai, Guangyan, Xie, Yuansheng, Hong, Quan, Fu, Bo, Chen, Xiangmei
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648526/
https://ncbi.nlm.nih.gov/pubmed/23667674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063799
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky