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Removal of alleles by genome editing (RAGE) against deleterious load
BACKGROUND: In this paper, we simulate deleterious load in an animal breeding program, and compare the efficiency of genome editing and selection for decreasing it. Deleterious variants can be identified by bioinformatics screening methods that use sequence conservation and biological prior informat...
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| Publicado no: | Genet Sel Evol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6472060/ https://ncbi.nlm.nih.gov/pubmed/30995904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-019-0456-8 |
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