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Targeting the ERK Signaling Pathway in Melanoma
The discovery of the role of the RAS/RAF/MEK/ERK pathway in melanomagenesis and its progression have opened a new era in the treatment of this tumor. Vemurafenib was the first specific kinase inhibitor approved for therapy of advanced melanomas harboring BRAF-activating mutations, followed by dabraf...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6472057/ https://ncbi.nlm.nih.gov/pubmed/30934534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20061483 |
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