Stereo-Selective Pharmacokinetics of Ilimaquinone Epimers Extracted from a Marine Sponge in Rats

An ilimquinone (IQ) mixture isolated from Hippiospongia metachromia, consisting of IQ and epi-ilimaquinone (epi-IQ), exerts anti-HIV, anti-microbial, anti-inflammatory, and anti-cancer effects. An HPLC-MS/MS method was developed for simultaneous determination of the two epimers in rat plasma, separa...

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Veröffentlicht in:Mar Drugs
Hauptverfasser: Son, Heebin, Noh, Keumhan, Park, InWha, Na, MinKyun, Oh, Sangtaek, Shin, Beom Soo, Kang, Wonku
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472033/
https://ncbi.nlm.nih.gov/pubmed/30884884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17030171
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