Ilimaquinone and Ethylsmenoquinone, Marine Sponge Metabolites, Suppress the Proliferation of Multiple Myeloma Cells by Down-Regulating the Level of β-Catenin

Deregulation of Wnt/β-catenin signaling promotes the development of a broad range of human cancers, including multiple myeloma, and is thus a potential target for the development of therapeutics for this disease. Here, we used a cell-based reporter system to demonstrate that ilimaquinone and ethylsm...

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Main Authors: Park, Seoyoung, Yun, Eunju, Hwang, In Hyun, Yoon, Soojin, Kim, Dong-Eun, Kim, Ji Seon, Na, MinKyun, Song, Gyu-Yong, Oh, Sangtaek
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071574/
https://ncbi.nlm.nih.gov/pubmed/24879546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12063231
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