GenHap: a novel computational method based on genetic algorithms for haplotype assembly

BACKGROUND: In order to fully characterize the genome of an individual, the reconstruction of the two distinct copies of each chromosome, called haplotypes, is essential. The computational problem of inferring the full haplotype of a cell starting from read sequencing data is known as haplotype asse...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Bioinformatics
Main Authors: Tangherloni, Andrea, Spolaor, Simone, Rundo, Leonardo, Nobile, Marco S., Cazzaniga, Paolo, Mauri, Giancarlo, Liò, Pietro, Merelli, Ivan, Besozzi, Daniela
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471693/
https://ncbi.nlm.nih.gov/pubmed/30999845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2691-y
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