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GenHap: a novel computational method based on genetic algorithms for haplotype assembly

BACKGROUND: In order to fully characterize the genome of an individual, the reconstruction of the two distinct copies of each chromosome, called haplotypes, is essential. The computational problem of inferring the full haplotype of a cell starting from read sequencing data is known as haplotype asse...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Tangherloni, Andrea, Spolaor, Simone, Rundo, Leonardo, Nobile, Marco S., Cazzaniga, Paolo, Mauri, Giancarlo, Liò, Pietro, Merelli, Ivan, Besozzi, Daniela
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471693/
https://ncbi.nlm.nih.gov/pubmed/30999845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2691-y
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