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Identification of Bis-Cyclic Guanidines as Antiplasmodial Compounds from Positional Scanning Mixture-Based Libraries

The screening of more than 30 million compounds derived from 81 small molecule libraries built on 81 distinct scaffolds identified pyrrolidine bis-cyclic guanidine library (TPI-1955) to be one of the most active and selective antiplasmodial libraries. The screening of the positional scanning library...

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Xehetasun bibliografikoak
Argitaratua izan da:Molecules
Egile Nagusiak: Perry, David L., Roberts, Bracken F., Debevec, Ginamarie, Michaels, Heather A., Chakrabarti, Debopam, Nefzi, Adel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471430/
https://ncbi.nlm.nih.gov/pubmed/30897744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24061100
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