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Autophosphorylation of Orphan Receptor ERBB2 Can Be Induced by Extracellular Treatment with Mildly Alkaline Media

ErbB2 is an oncogene receptor tyrosine kinase linked to breast cancer. It is a member of the epidermal growth factor receptor (EGFR) minifamily. ErbB2 is currently viewed as an orphan receptor since, by itself, it does not bind EGF-like ligands and can be activated only when overexpressed in maligna...

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Foilsithe in:Int J Mol Sci
Main Authors: Serova, Oxana V., Chachina, Natalia A., Gantsova, Elena A., Popova, Nadezhda V., Petrenko, Alexander G., Deyev, Igor E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470685/
https://ncbi.nlm.nih.gov/pubmed/30917575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20061515
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