Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice

The underlying pathogenesis of chronic kidney disease involves an activated renin-angiotensin system and systemic inflammation which ultimately develop renal injury. Rikkunshito (RKT) has been reported to exert anti-fibrotic and anti-inflammatory effects through enhancement of ghrelin signaling path...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Azushima, Kengo, Uneda, Kazushi, Wakui, Hiromichi, Ohki, Kohji, Haruhara, Kotaro, Kobayashi, Ryu, Haku, Sona, Kinguchi, Sho, Yamaji, Takahiro, Minegishi, Shintaro, Ishigami, Tomoaki, Yamashita, Akio, Tamura, Kouichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470237/
https://ncbi.nlm.nih.gov/pubmed/30996242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42657-1
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