Effects of ATRAP in Renal Proximal Tubules on Angiotensin‐Dependent Hypertension

BACKGROUND: We have previously shown that ATRAP (angiotensin II receptor–associated protein; Agtrap) interacts with AT1R (angiotensin II type 1 receptor) and promotes constitutive internalization of AT1R so as to inhibit hyperactivation of its downstream signaling. In response to angiotensin II, sys...

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Bibliographic Details
Published in:J Am Heart Assoc
Main Authors: Kinguchi, Sho, Wakui, Hiromichi, Azushima, Kengo, Haruhara, Kotaro, Koguchi, Tomoyuki, Ohki, Kohji, Uneda, Kazushi, Matsuda, Miyuki, Haku, Sona, Yamaji, Takahiro, Yamada, Takayuki, Kobayashi, Ryu, Minegishi, Shintaro, Ishigami, Tomoaki, Yamashita, Akio, Fujikawa, Tetsuya, Tamura, Kouichi
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507205/
https://ncbi.nlm.nih.gov/pubmed/30977419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.012395
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