Angiotensin II Type 1 Receptor‐Associated Protein Regulates Kidney Aging and Lifespan Independent of Angiotensin

BACKGROUND: The kidney is easily affected by aging‐associated changes, including glomerulosclerosis, tubular atrophy, and interstitial fibrosis. Particularly, renal tubulointerstitial fibrosis is a final common pathway in most forms of progressive renal disease. Angiotensin II type 1 receptor (AT1R)...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Uneda, Kazushi, Wakui, Hiromichi, Maeda, Akinobu, Azushima, Kengo, Kobayashi, Ryu, Haku, Sona, Ohki, Kohji, Haruhara, Kotaro, Kinguchi, Sho, Matsuda, Miyuki, Ohsawa, Masato, Minegishi, Shintaro, Ishigami, Tomoaki, Toya, Yoshiyuki, Atobe, Yoshitoshi, Yamashita, Akio, Umemura, Satoshi, Tamura, Kouichi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586453/
https://ncbi.nlm.nih.gov/pubmed/28751545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006120
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