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Delayed maturation of GABAergic signaling in the Scn1a and Scn1b mouse models of Dravet Syndrome

Dravet syndrome (DS) is a catastrophic developmental and epileptic encephalopathy characterized by severe, pharmacoresistant seizures and the highest risk of Sudden Unexpected Death in Epilepsy (SUDEP) of all epilepsy syndromes. Here, we investigated the time course of maturation of neuronal GABAerg...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Yuan, Yukun, O’Malley, Heather A., Smaldino, Melissa A., Bouza, Alexandra A., Hull, Jacob M., Isom, Lori L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470170/
https://ncbi.nlm.nih.gov/pubmed/30996233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42191-0
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