β1-C121W Is Down But Not Out: Epilepsy-Associated Scn1b-C121W Results in a Deleterious Gain-of-Function

Voltage-gated sodium channel (VGSC) β subunits signal through multiple pathways on multiple time scales. In addition to modulating sodium and potassium currents, β subunits play nonconducting roles as cell adhesion molecules, which allow them to function in cell–cell communication, neuronal migratio...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kruger, Larisa C., O'Malley, Heather A., Hull, Jacob M., Kleeman, Amanda, Patino, Gustavo A., Isom, Lori L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899524/
https://ncbi.nlm.nih.gov/pubmed/27277800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0405-16.2016
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