Protective Epitope Discovery and Design of MUC1-based Vaccine for Effective Tumor Protections in Immunotolerant Mice

Human mucin-1 (MUC1) is a highly attractive antigen for the development of anticancer vaccines. However, in human clinical trials of multiple MUC1 based vaccines, despite the generation of anti-MUCl antibodies, the antibodies often failed to exhibit much binding to tumor presumably due to the challe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Wu, Xuanjun, Yin, Zhaojun, McKay, Craig, Pett, Christian, Yu, Jin, Schorlemer, Manuel, Gohl, Trevor, Sungsuwan, Suttipun, Ramadan, Sherif, Baniel, Claire, Allmon, Anthony, Das, Rupali, Westerlind, Ulrika, Finn, M. G., Huang, Xuefei
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470043/
https://ncbi.nlm.nih.gov/pubmed/30398345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08473
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados