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Antitumor Humoral and T Cell Responses by Mucin-1 Conjugates of Bacteriophage Qβ in Wild-type Mice

Mucin-1 (MUC1) is one of the top ranked tumor associated antigens. In order to generate effective anti-MUC1 immune responses as potential anticancer vaccines, MUC1 peptides and glycopeptides have been covalently conjugated to bacteriophage Qβ. Immunization of mice with these constructs led to highly...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Yin, Zhaojun, Wu, Xuanjun, Kaczanowska, Katarzyna, Sungsuwan, Suttipun, Aragones, Marta Comellas, Pett, Christian, Yu, Jin, Baniel, Claire, Westerlind, Ulrika, Finn, M.G., Huang, Xuefei
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082418/
https://ncbi.nlm.nih.gov/pubmed/29782143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00313
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