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Unique features in the intracellular transport of typhoid toxin revealed by a genome-wide screen
Typhoid toxin is a virulence factor for Salmonella Typhi and Paratyphi, the cause of typhoid fever in humans. This toxin has a unique architecture in that its pentameric B subunit, made of PltB, is linked to two enzymatic A subunits, the ADP ribosyl transferase PltA and the deoxyribonuclease CdtB. T...
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| Udgivet i: | PLoS Pathog |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6469816/ https://ncbi.nlm.nih.gov/pubmed/30951565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007704 |
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