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Unique features in the intracellular transport of typhoid toxin revealed by a genome-wide screen

Typhoid toxin is a virulence factor for Salmonella Typhi and Paratyphi, the cause of typhoid fever in humans. This toxin has a unique architecture in that its pentameric B subunit, made of PltB, is linked to two enzymatic A subunits, the ADP ribosyl transferase PltA and the deoxyribonuclease CdtB. T...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Chang, Shu-Jung, Jin, Sheng Chih, Jiao, Xuyao, Galán, Jorge E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469816/
https://ncbi.nlm.nih.gov/pubmed/30951565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007704
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