Generation and Characterization of Typhoid Toxin-Neutralizing Human Monoclonal Antibodies

Typhoid toxin is a virulence factor of Salmonella enterica serovar Typhi, the causative agent of typhoid fever, and is thought to be responsible for the symptoms of severe disease. This toxin has a unique A2B5 architecture with two active subunits, the ADP ribosyl transferase PltA and the DNase CdtB...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Jiao, Xuyao, Smith, Sarah, Stack, Gabrielle, Liang, Qi, Bradley, Allan, Kellam, Paul, Galán, Jorge E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504945/
https://ncbi.nlm.nih.gov/pubmed/32661121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00292-20
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