Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines

In eukaryotes, double-stranded (ds) RNA induces sequence-specific inhibition of gene expression, referred to as RNA interference (RNAi). In invertebrates, RNAi can be triggered effectively by either long dsRNAs or 21- to 23-nt-long short interfering (si) duplex RNAs, acting as effectors of RNAi. siR...

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Billy, Eric, Brondani, Vincent, Zhang, Haidi, Müller, Ulrich, Filipowicz, Witold
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2001
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64698/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11724966/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.261562698
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