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Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines

In eukaryotes, double-stranded (ds) RNA induces sequence-specific inhibition of gene expression, referred to as RNA interference (RNAi). In invertebrates, RNAi can be triggered effectively by either long dsRNAs or 21- to 23-nt-long short interfering (si) duplex RNAs, acting as effectors of RNAi. siR...

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Main Authors: Billy, Eric, Brondani, Vincent, Zhang, Haidi, Müller, Ulrich, Filipowicz, Witold
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC64698/
https://ncbi.nlm.nih.gov/pubmed/11724966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261562698
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