The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

gp78, also known as the tumor autocrine motility factor receptor, is a transmembrane protein whose expression is correlated with tumor metastasis. We establish that gp78 is a RING finger-dependent ubiquitin protein ligase (E3) of the endoplasmic reticulum (ER). Consistent with this, gp78 specificall...

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Detalles Bibliográficos
Main Authors: Fang, Shengyun, Ferrone, Marco, Yang, Cuihong, Jensen, Jane P., Tiwari, Swati, Weissman, Allan M.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC64697/
https://ncbi.nlm.nih.gov/pubmed/11724934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251401598
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