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Regulation of mitophagy by the Gp78 E3 ubiquitin ligase
Glycoprotein 78 (Gp78) is a critical E3 ubiquitin ligase in endoplasmic reticulum–associated degradation. Overexpression of Flag-tagged Gp78 (Flag-gp78), but not Flag-gp78 mutated in its RING-finger domain (Flag-RINGmut) with deficient ubiquitin ligase activity, induces mitochondrial fragmentation a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623636/ https://ncbi.nlm.nih.gov/pubmed/23427266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-08-0607 |
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