Regulation of mitophagy by the Gp78 E3 ubiquitin ligase

Glycoprotein 78 (Gp78) is a critical E3 ubiquitin ligase in endoplasmic reticulum–associated degradation. Overexpression of Flag-tagged Gp78 (Flag-gp78), but not Flag-gp78 mutated in its RING-finger domain (Flag-RINGmut) with deficient ubiquitin ligase activity, induces mitochondrial fragmentation a...

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Bibliographic Details
Main Authors: Fu, Min, St-Pierre, Pascal, Shankar, Jay, Wang, Peter T. C., Joshi, Bharat, Nabi, Ivan R.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2013
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623636/
https://ncbi.nlm.nih.gov/pubmed/23427266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-08-0607
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