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Pirarubicin reduces USP22 expression by inhibiting CREB-1 phosphorylation in HeLa cells

The expression of ubiquitin specific peptidase 22 (USP22) is upregulated in several types of cancer, and has been implicated in tumorigenesis. Pirarubicin (THP), an anthracycline antineoplastic drug, can induce apoptosis of several types of cancer cells. However, the molecular mechanisms underlying...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zhou, Xiaoou, Gan, Lijun, Liu, Jianyun, Xie, Xin, Wang, Tao, Xiong, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468931/
https://ncbi.nlm.nih.gov/pubmed/31007754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7447
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